Aaron Lin

About

Work

Princeton University
|

Postdoc

US

Education

Harvard University
United States of America

Ph.D.

Princeton University
United States of America

A.B.

Publications

*Natural history of Ebola virus disease in rhesus monkeys shows viral variant emergence dynamics and tissue-specific host responses.

Published by

Cell genomics. Co-last author

Summary

journal-article

Membrane-proximal motifs encode differences in signaling strength between type I and III interferon receptors.

Published by

Science signaling

Summary

journal-article

Single-cell massively-parallel multiplexed microbial sequencing (M3-seq) identifies rare bacterial populations and profiles phage infection.

Published by

Nature microbiology

Summary

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Single-cell profiling of lncRNA expression during Ebola virus infection in rhesus macaques.

Published by

Nature communications

Summary

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Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events.

Published by

Science

Summary

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*Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics.

Published by

Cell. Co-first author

Summary

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SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses.

Published by

Cell

Summary

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Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time.

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Nature Communications

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*Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111.

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Viruses. Co-first author

Summary

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Programmable Inhibition and Detection of RNA Viruses Using Cas13.

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Molecular Cell

Summary

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Capturing sequence diversity in metagenomes with comprehensive and scalable probe design.

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Nature Biotechnology

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Field validation of recombinant antigen immunoassays for diagnosis of Lassa fever.

Published by

Scientific Reports

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*Evidence of Ebola Virus Replication and High Concentration in Semen of a Patient During Recovery.

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Clinical Infectious Diseases. Co-first author

Summary

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Zika virus evolution and spread in the Americas.

Published by

Nature

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*Ebola Virus Glycoprotein with Increased Infectivity Dominated the 2013-2016 Epidemic.

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Cell. Co-first author

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In vivo Ebola virus infection leads to a strong innate response in circulating immune cells.

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BMC Genomics

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Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus.

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Cell

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Ebola Virus Epidemiology, Transmission, and Evolution during Seven Months in Sierra Leone.

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Cell

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DNA methyltransferase DNMT3A associates with viral proteins and impacts HSV-1 infection.

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Proteomics

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Evaluation of the potential impact of Ebola virus genomic drift on the efficacy of sequence-based candidate therapeutics.

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mBio

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*A proteomic perspective of inbuilt viral protein regulation: pUL46 tegument protein is targeted for degradation by ICP0 during herpes simplex virus type 1 infection.

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Molecular & Cellular Proteomics. First author

Summary

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Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).

Published by

Journal of Immunology

Summary

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