Aaron Lin

Work

Princeton University

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Postdoc

US

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Education

Harvard University

United States of America
→
Ph.D.

Princeton University

United States of America
→
A.B.

Publications

*Natural history of Ebola virus disease in rhesus monkeys shows viral variant emergence dynamics and tissue-specific host responses.

Cell genomics. Co-last author

journal-article

Membrane-proximal motifs encode differences in signaling strength between type I and III interferon receptors.

Science signaling

journal-article

Single-cell massively-parallel multiplexed microbial sequencing (M3-seq) identifies rare bacterial populations and profiles phage infection.

Nature microbiology

journal-article

Single-cell profiling of lncRNA expression during Ebola virus infection in rhesus macaques.

Nature communications

journal-article

*Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111.

Viruses. Co-first author

journal-article

Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time.

Nature Communications

journal-article

Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events.

Science

journal-article

*Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics.

Cell. Co-first author

journal-article

SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses.

Cell

journal-article

Programmable Inhibition and Detection of RNA Viruses Using Cas13.

Molecular Cell

journal-article

Capturing sequence diversity in metagenomes with comprehensive and scalable probe design.

Nature Biotechnology

journal-article

Field validation of recombinant antigen immunoassays for diagnosis of Lassa fever.

Scientific Reports

journal-article

*Evidence of Ebola Virus Replication and High Concentration in Semen of a Patient During Recovery.

Clinical Infectious Diseases. Co-first author

journal-article

Zika virus evolution and spread in the Americas.

Nature

journal-article

*Ebola Virus Glycoprotein with Increased Infectivity Dominated the 2013-2016 Epidemic.

Cell. Co-first author

journal-article

In vivo Ebola virus infection leads to a strong innate response in circulating immune cells.

BMC Genomics

journal-article

Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus.

Cell

journal-article

Ebola Virus Epidemiology, Transmission, and Evolution during Seven Months in Sierra Leone.

Cell

journal-article

DNA methyltransferase DNMT3A associates with viral proteins and impacts HSV-1 infection.

Proteomics

journal-article

Evaluation of the potential impact of Ebola virus genomic drift on the efficacy of sequence-based candidate therapeutics.

mBio

journal-article

*A proteomic perspective of inbuilt viral protein regulation: pUL46 tegument protein is targeted for degradation by ICP0 during herpes simplex virus type 1 infection.

Molecular & Cellular Proteomics. First author

journal-article

Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).

Journal of Immunology

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